Harrison's Manual of Medicine 17/e

Table 131-3: Drugs for Treatment of Acute Heart Failure

Table 131-3

Initiating Dose

Maximal Dose

Vasodilators

Nitroglycerin

20 μg/min

40-400 μg/min

Nitroprusside

10 μg/min

30-350 μg/min

Nesiritide

Bolus 2 μg/kg

0.01-0.03 μg/kg per mina

Inotropes

Dobutamine

1-2 μg/kg per min

2-10 μg/kg per minb

Milrinone

Bolus 50 μg/kg

0.1-0.75 μg/kg per minb

Dopamine

1-2 μg/kg per min

2-4 μg/kg per minb

Levosimendan

Bolus 12 μg/kg

0.1-0.2 μg/kg per minc

Vasoconstrictors

Dopamine for hypotension

5 μg/kg per min

5-20 μg/kg per min

Epinephrine

0.5 μg/kg per min

50 μg/kg per min

Phenylephrine

0.3 μg/kg per min

3 μg/kg per min

Vasopressin

0.05 units/min

0.1-0.4 units/min


aUsually < 4 μg/kg/min.
bInotropes will also have vasodilatory properties.
cApproved outside of the United States for the management of acute heart failure.


Chapter:

Congestive Heart Failure and Cor Pulmonale

Table 131-3: Drugs for Treatment of Acute Heart Failure has been found in Harrison's Manual of Medicine 17/e

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